We are TTS Research, an independent and dedicated multi-specialty research center that collaborates closely with local physicians. Located in the heart of the picturesque Texas Hill Country, just outside of San Antonio, our facility is strategically positioned to provide exceptional care. Our mission at TTS Research is to provide respiratory care to our community free of charge. Regardless of whether individuals participate in our studies, we are dedicated to ensuring accessible and high-quality respiratory care.

Founder and Director

Mary Jimenez

TTS Research was founded in 2003 by Mary Jimenez. Her goal is to bring education to people with existing health conditions and provide patients with state-of-the-art medications to help manage their medical needs.

Mary is 100% dedicated to improving the quality of life for people through medical options, regardless of their social or economic standing, or ability to afford medical care. She has dedicated over 20 years towards the successful conduction of over 120 clinical trials in Boerne Texas. Mary proudly served in the United States Army National Guard as an Army nurse. Her community involvement includes 20 years of volunteer service for Hill Country Animal League, a local SPCA. Her strongest and proudest achievements are related to her family.




About David Fuentes

Dr. David Fuentes received his undergraduate degree from the University of Texas at Austin in 1987. He graduated from the University Texas Health Science Center at San Antonio in 1991.


Dr. Fuentes additionally completed a fellowship in Allergy and Immunology at Baylor University College of Medicine, Texas Children’s Hospital in 1996. Under the blanket of Immunology, he participated in numerous Pediatric HIV trials for both inpatient and outpatient care. He holds board certifications with the American Board of Allergy & Immunology, and the American Board of Pediatrics and remains recertified in both specialties. He is a fellow of the American College of Allergy Asthma and Immunology and a member of the San Antonio Allergy Asthma and Immunology Society.


Dr. Fuentes has devoted over 20 years to the success of over 120 clinical research trials. His primary focus includes Allergy, Asthma, Immunology, COPD, Chronic Bronchitis, Emphysema, Atopic Dermatitis, Eczema, and many other immune system-related disorders. He treats pediatric, adolescent, and adult patients for Asthma, Allergies, and Immunology.

Additional research experience includes a National Coordinator and Key Opinionator for Clinical Research Trials as of 2019.  

Is certified under the Federal Wide Assurance (FWA) for the Protection of Human Subjects. 

  • Completed and updates training for: 
  • Good Clinical Practice, International Committee of Harmonization, Belmont Report, Nuremberg Code
  • FDA Form 1572
  • Adverse Event and Serious Adverse Event Reporting
  • Informed Consent Process and Principal Investigator Responsibilities 
  • Informed Assent Process 


In early 2021, Dr. Fuentes served as a facilitator/Medical Director for a medical Mobil treatment unit used specifically to treat COVID 19 positive patients and prevent cross contamination from positive patients to healthy patients. The use of this Mobil clinic was especially crucial with the new variants of COVID 19 and to reach patients who were not adequately served during the pandemic. 

Served as a facilitator/Medical  Director for the distribution of COVID 19 vaccines for the local community during the COVID 19 pandemic.



About Dr. Ian Alexander

Dr. Ian Alexander, M.D., Investigator, is a board-certified Otolaryngologist. He specializes in diseases of the ears, nose, and throat, and balloon sinuplasty.


 Dr. Alexander has conducted clinical research trials with TTS Research as of 2016. He is experienced in respiratory studies for pediatrics, adolescents, and adults and has participated in over 50 studies. 




    About Dr. Lisa Welchel
    Lisa Whelchel, APRN, FNP-C had actively served her country through the United States Military and has participated in Clinical Research for over 14 years, serving as a Sub-Investigator in over 60 clinical trials.


    Welcome to TTS Research, where exceptional healthcare meets serenity. Our 8400-square-foot building in Boerne, Texas, is not just any facility – it’s a haven designed to enhance your clinical research experience. Step into our comfortable patient lounge, complete with a large flat-screen television, a patient massage chair, and a luxurious leather couch. As you relax, immerse yourself in the mesmerizing beauty of our 300-gallon saltwater exotic fish tank. Indulge in the aromatic delights of our coffee bar and bask in the tranquility of our patient leisure area, which opens up to an inviting wrap-around porch and garden. At TTS Research, we believe in creating a nurturing environment that supports your journey towards better health. 

    We are on Instagram
    Expressing our gratitude this Thanksgiving Season! We can hardly contain our excitement for Thanksgiving! We want to extend a heartfelt thank you to the TTS Patients, who are forever a part of our family. We hope you enjoy this special season as much as we do, and please know how truly grateful we are for each and every one of you. Wishing you and yours a blessed holiday 🍂🍁🥧💛🧡🦃 our office will be closing today at 12pm Wednesday, 22 November and will remain closed until Friday, 24 November (Emergency After Hours Answering Service) 830.446.0882.  #boernehealth #boerneasthma #boernetexas #boernechamber #boerneriverroad #boernewindmills #boernelove #boernewomenowned #boernewomenownedbusiness
    We would like to take a moment to share our gratitude for those who attended our 20th Anniversary Ribbon Cutting Ceremony and Military Wall Open House. We extend our sincere thanks to everyone who joined us to celebrate this significant milestone. Your presence made the occasion even more special. We appreciate our community’s support and trust in us to share the history of those in service to our country. We would like to extend a special thank you to the Boerne Chamber of Commerce, the San Antonio Buffalo Soldiers, and Ed’s Smok-N-Q BBQ for their contributions to this event! #boernechamber #boernechamberofcommmerce #boerneradio #boernetx #boernestrong #boernehealth #boernecommunity #freehealthcare #20yearanniversary❤️ #beautifulcommunity
    Each person on this wall has a family, story, and life we want to honor! This wall is a legacy, a piece of history, and a way to share the remarkable stories of those who have fought for our freedom. Those who are currently fighting or have served in the past, this wall is a space for those to be remembered. Please join us for our ribbon cutting ceremony this Thursday at 1:30pm #ribboncutting✂️ #boernechamberofcommerce #boernetexas #boerneveterans #boerneriverroad #boernetx #visitboerne #boernehealthcare #boernehealth
    Please Join Us For Our: RIBBON CUTTING CEREMONY & PRESENTATION OF OUR MILITARY WALL 🇺🇸 celebrating TTS Research’s 20th Anniversary  Date & Time: Thursday OCT 26, 2023 at 1:30pm  Please Join us After for Refreshments & Hor d’oeuvres #boernechamberofcommerce #boernetexas #boerneriverroad #boerneribboncutting #boernehealthcare #allarewelcome #womenownedbusiness
    We absolutely adore all of our patients! They are family to us! Here is a great sneak peak at the behind the scenes with Dr.Fuentes! Here he is listening to our patient’s lungs and heart! We would love to have you come in and check your lungs. We offer compensation for all check-up and no insurance is required. #boernetexas #boernelife #visitboerne #boernemainstreet #boernestrong #boernehealth #boernemoms #boerneriverroad
    Boerne Market Days! Come visit us and grab a ice cold water, koozie, candy, and learn about our studies we are currently offering! We hope to see you tomorrow and Sunday ❤️
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