Clinical studies are research studies in which people participate as volunteers. Clinical research studies (sometimes called trials or protocols) are a means of developing new and upcoming treatments and medications for diseases and conditions. There are strict rules for clinical trials, which are monitored closely by the National Institutes of Health and the U.S. Food and Drug Administration. Some of the research studies at TTS Research involve promising new treatments that may directly benefit patients.

Participants in clinical research trials often find the experience to be positive and rewarding in many ways:

• The opportunity to contribute to science for the development of new therapies and to improve our understanding of existing therapies and diseases.

• Receive close medical attention and evaluation by well trained, friendly health professionals. 
• Receive diagnostic testing, evaluation, and treatment at no cost to the patient.
• Receive compensation for time and travel in the form of a stipend.
• Learn more about your medical condition and potential treatment options. 

Thanks to thousands of individuals like you who take part in clinical research, scientific and technological advances have improved health outcomes for millions of people. The role of volunteers in clinical research is crucial in the quest for knowledge that will improve the health of future generations. Without your help, the research studies at the Clinical Center cannot be accomplished.

Many of the respiratory medications on the market today for Asthma and COPD have been tested at our facility. Our physicians carefully review the clinical trials offered to our facility and only chose studies that will potentially be beneficial to patients in our community.

Patient participation is always voluntary, and patients can choose to withdraw at any time, for any reason.  Our staff will answer any question you may have in a friendly, professional manner and will strive to make your visit as pleasant as possible.

Phase I studies aim to determine the ‘maximum tolerated dose’ of a drug, ensuring it doesn’t cause unacceptable side effects. During these studies, patient volunteers are primarily monitored for side effects rather than the drug’s impact on their disease. Initially, a small group of volunteers is administered low doses of the trial drug to assess its tolerance and how it functions in the body. Subsequently, larger doses are given to the next group of volunteers.  Phase I studies typically offer minimal or no direct benefits to the participants, Phase II studies involve a larger number of individuals. These studies delve deeper into how a drug operates within the body, evaluating its efficacy in treating specific conditions and identifying potential side effects. Some volunteer subjects may benefit from participating in Phase II studies. Phase III studies compare new drugs against commonly used ones. Some participants receive the new drug while others receive the standard drug. The trial is designed to determine how a new drug can contribute to the management of a particular condition. 

Participating in clinical research carries inherent risks, just like any other facet of medical care. It’s crucial to consider two key aspects when evaluating these risks: the potential harm resulting from study participation and the likelihood of any harm occurring. While most clinical studies involve minor discomfort that subsides quickly, some volunteers may encounter complications necessitating medical attention. Before engaging in research, you will receive a detailed consent document outlining the specific risks associated with the study. Additionally, a knowledgeable member of the research team will provide thorough explanations and address any concerns you may have. It’s essential to carefully weigh these risks before making a participation decision. Although direct personal benefits may not be guaranteed, your involvement can provide valuable insights that may ultimately benefit others.